SMALL PENETRATION INHIBITING MOLECULES Russian patent published in 2010 - IPC C07C233/81 A61K31/16 

FIELD: chemistry.

SUBSTANCE: present invention relates to a formula (III)

compound, where R¹ is a radical of formula (II), , R² is bromine, chlorine, C_1-6alkyl, C_1-6alkyloxy, where the said R² radicals are in the formula (III) compound, with respect to group Y in the meta-, para-positions; n equals 1; Y is -C(=O)- or -S(=O)₂-; R³ is hydroxy; R⁴ is hydrogen; X is -CH₂-; each R⁶ is independently R⁷-C(=O)-, R⁸-S(=O)₂-NH- or R⁸-C(=O)-NH-, where substitutes R⁶ are bonded in the meta- and para-positions, or in the ortho- and meta-positions; R⁷ is hydroxy; R⁸ is phenyl which is substituted with a halogen, C_1-6 alkyl, C_1-6 alkoxy, where the substitutes are in the meta- or para-position relative the point where the phenyl group is bonded; and m equals 2, as well as to pharmaceutical compositions which inhibit penetration of HIV into cells containing the said compound, and to a novel compound 3'-methylene-bis(6-((4-methylpheny)sulfonylamino)-benzoic acid).

EFFECT: possibility of preparing pharmaceutical compositions which inhibit penetration of HIV into cells.

4 cl, 4 ex, 1 tbl