FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to biotechnology, virology and medicine. Vaccines can be used to treat individuals chronically infected with HIV by inducing a protective cell-mediated response in these individuals against the same HIV subtype which was used to make the vaccine. Invention can be used in medicine.
EFFECT: obtaining an intact human immunodeficiency virus of a defined subtype which can be used in making vaccines and pharmaceutical compositions containing such vaccines.
21 cl, 2 dwg, 4 ex
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