METHOD FOR THERAPY OF MALIGNANT TUMOUR Russian patent published in 2016 - IPC C07K7/00 A61K38/10 A61P35/00 

Abstract RU 2577993 C2

FIELD: medicine.

SUBSTANCE: presented inventions refer to biomedicine and concern a peptide having an ability to bind COMM domain, using it for producing compositions. The characterised peptide consists of the amino acid sequence HARIKpTFRRIKWKYKGKFW, wherein N-terminal is protected by acetylation, whereas D-amino acids present in positions of prolin-6 and leucine-11.

EFFECT: presented group of inventions allows treating malignant tumours by increasing a nuclear localisation of COMMD1 protein, which is associated with a decrease or blocking of malignant tumour cell proliferation.

7 cl, 9 dwg, 2 tbl, 10 ex

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RU 2 577 993 C2

Authors

Gerra Valespi Maribel

Fernandes Masso Khulio Raul

Musakchio Lasa Aleksis

Khil Valdes Kheovanis

Rejes Akosta Osvaldo

Oliva Argeles Brisajda Majlin

Dates

2016-03-20Published

2011-05-31Filed