NEW PHTHALAZINONE DERIVATIVES AS AURORA A KINASE INHIBITORS Russian patent published in 2010 - IPC C07D403/12 A61K31/502 A61P35/00 

Abstract RU 2397166 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are described compounds of formula I: , their pharmaceutically acceptable salts where R1-R7, Y and n are specified in the patent claim. The compounds exhibit inhibitory action in the relation to aurora A tyrosine kinase. There is also described a drug of the compound of formula (I). The drug can be used for control or prevention of diseases, such as cancer.

EFFECT: preparation of new phthalazinone derivatives which can be used for control or prevention of diseases, such as cancer.

17 cl, 2 tbl, 41 ex

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RU 2 397 166 C2

Authors

Bojd Ehduard

Brukfild Frederik

Zhorzh Gi

Goller Bernkhard

Khjunsh Zabine

Rjuger Petra

Rjut Mattias

Shajblikh Shtefan

Shjull' Kristine

Fon-Der-Zal Vol'Fgang

Uorn Dzhastin

Vajgand Shtefan

Dates

2010-08-20Published

2005-09-23Filed