FIELD: medicine.
SUBSTANCE: claimed group of inventions relates to medicine, namely to endocrinology, and deals with regulation of fat in organism. For this purpose stabilisation of alpha subunit of hypoxia-induced factor protein (HIFα) is realised. In order to stabilise HIFα efficient amounts of compound inhibiting HIF hydroxylase activity, representing 2-oxoglutarate-dioxygenase mimetic are introduced.
EFFECT: inventions ensure reduction of fat formation and deposition due to regulation of its metabolism.
31 cl, 11 dwg, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DIABETES TREATMENT | 2003 |
|
RU2363465C2 |
| FAT CONTENT CONTROL | 2003 |
|
RU2346688C2 |
| APPLICATION OF STABILISERS OF HIF- ALPHA FOR INTENSIFICATION OF ERYTHROPOIESIS | 2004 |
|
RU2414214C2 |
| NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND USE THEREOF IN INCREASING ENDOGENOUS ERYTHROPOIETIN | 2004 |
|
RU2379291C2 |
| CYANOISOQUINOLINE COMPOUNDS (VERSIONS), PHARMACEUTICAL COMPOSITION BASED THEREON, HYPOXIA-INDUCIBLE FACTOR (HIF) HYDROXYLASE INHIBITING METHOD AND METHOD OF TREATING AND/OR PREVENTING HIF-ASSOCIATED CONDITION AND/OR ERYTHROPOIETIN-AND/OR ANAEMIA-ASSOCIATED CONDITION | 2007 |
|
RU2457204C2 |
| PROLYL HYDROXYLASE INHIBITORS AND APPLICATION METHODS THEREOF | 2007 |
|
RU2429226C9 |
| AMIDE DERIVATIVES CARRYING CYCLOPROPYLAMINOCARBONYL SUBSTITUTE, SUITABLE AS CYTOKINE INHIBITORS | 2004 |
|
RU2382028C2 |
| COMPOUNDS AND COMPOSITIONS FOR STABILISATION OF HYPOXIA INDUCED FACTOR-2 ALPHA AS METHOD OF CANCER MEDICAL TREATMENT | 2012 |
|
RU2602498C2 |
| CATECHOL-O-METHYL TRANSFERASE INHIBITORS AND USE THEREOF IN TREATING PSYCHOTIC DISORDERS | 2011 |
|
RU2586974C2 |
| PYRROLO- AND THIAZOLOPYRIDINE COMPOUNDS (VERSIONS) AND BASED PHARMACEUTICAL COMPOSITION | 2007 |
|
RU2461557C2 |
