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2 461 557

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IPC

C07D471/04(2006-01-01)

C07D513/04(2006-01-01)

A61K31/429(2006-01-01)

A61K31/4353(2006-01-01)

A61P7/06(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2008143564/04, 2007-04-04

(24)

Start date

2007-04-04

(22)

Actual filing date

2007-04-04

(45)

Published

2012-09-20

(72)

Inventor

Arend Majkl P.Vu Min'Dehn ShaotszjanTertl Ehrik D.Flippin Li Eh.Kho Vehn'-Bin'Chehn Khehn

(73)

Holder

Fajbrodzhen, Ink.

PYRROLO- AND THIAZOLOPYRIDINE COMPOUNDS (VERSIONS) AND BASED PHARMACEUTICAL COMPOSITION Russian patent published in 2012 - IPC C07D471/04 C07D513/04 A61K31/429 A61K31/4353 A61P7/06 A61P9/10

Abstract RU 2461557 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention describes the pyrrolo- and thiazolopyridinium compounds and their pharmaceutically acceptable salts covered by general structural formula I: wherein the values A, B, R¹, R², R³, R⁴, R⁵, R⁶, R⁷ and R⁸ are those as presented in cl.1, and a pharmaceutical composition based on the given compound for inhibition of hypoxia-inducible factor (HIF) hydroxylase activity.

EFFECT: there are produced and described new compounds able to modulate hypoxia-inducible factor (HIF) stability and/or activity.

29 cl, 178 ex

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RU 2 461 557 C2

Authors

Arend Majkl P.

Vu Min'

Dehn Shaotszjan

Tertl Ehrik D.

Flippin Li Eh.

Kho Vehn'-Bin'

Chehn Khehn

Dates

2012-09-20—Published

2007-04-04—Filed