FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmacology, namely to liquid compositions for treating hyperlipidemia, containing fenofibrate dissolved in an excipient which contains omega-3 fatty acid ether and ethanol, and optionally, a surface-active substance. Besides there is disclosed a method for improving fenofibrate solubility in omega-3 fatty acid ether that involves addition of ethanol to said omega-3 fatty acid ether, and also a methods of treating a patient suffering hyperlipidemia. Said improvement of fenofibrate solubility is ensured by the fact that the liquid compositions additionally contain ethanol in minimum amount 10 wt % of the composition weight. Besides a surface-active substance is optionally added to the liquid compositions specified above to ensure better digestion and reduced food intake effect.
EFFECT: improved bioavailability and higher effectiveness in small amount due to better fenofibrate solubility in omega-3 fatty acid ether.
27 cl, 32 tbl, 22 ex, 16 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| NOVEL PHARMACEUTICAL STATIN COMPOSITIONS AND TREATMENT METHODS CONNECTED WITH IT | 2005 |
|
RU2382642C2 |
| FODDER ADDITIVE AND ITS APPLICATION | 2008 |
|
RU2376865C1 |
| BIOLOGICAL MATERIALS AND USE THEREOF | 2011 |
|
RU2593709C2 |
| BAR SOAP COMPOSITION WITH REDUCED WEAR PROPERTIES | 2004 |
|
RU2356941C2 |
| METHOD FOR ISOMERISATION OF C-C PARAFFIN HYDROCARBONS | 2012 |
|
RU2470000C1 |
| BROILER CHICKENS FEEDING METHOD | 2010 |
|
RU2499408C2 |
| HEAT CARRIER | 2016 |
|
RU2656666C1 |
| CONFECTIONERY FUNCTIONAL MIXTURE FOR COOKIES | 2016 |
|
RU2626625C1 |
| SUBSTANCES WITH PREBIOTIC ACTION FOR APPLICATION IN DEODORANTS | 2005 |
|
RU2391091C2 |
| LIGHT-DIODE HARDENING OF RADIATION-CURABLE COVERING COMPOSITIONS OF OPTIC FIBRES | 2010 |
|
RU2554650C2 |
