NOVEL PORPHYRIN DERIVATIVES, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS AND USE THEREOF IN PHOTODYNAMIC THERAPY Russian patent published in 2010 - IPC C07D487/22 A61K31/409 A61P35/00 

Abstract RU 2399622 C2

FIELD: chemistry.

SUBSTANCE: invention relates to porphyrin derivatives of formula

and

, where X1, X2, X3, X4, X5, X6, X7, X8 denote halogen atoms or hydrogen atoms and R1, R2, R3, R4 are selected from OH-groups, amino acids, OR-groups, NHR-groups and/or chlorine atoms, where R is an alkyl containing 1-12 carbon atoms. The invention also relates to a method of obtaining said compounds and medicinal agents prepared from said compounds.

EFFECT: possibility of using compounds and medicinal agents in photodynamic therapy of cancerous diseases.

19 cl, 2 ex

Similar patents RU2399622C2

Title Year Author Number
ATROPISOMERS OF HALOGENATED TETRAPHENYLBACTERIOCHLORINS AND CHLORINS AND THEIR USE IN PHOTODYNAMIC THERAPY 2016
  • Ferrejra Gonsalves Nunu Paulu
  • Serka Martins Dush Santush Taniya Patrisiya
  • Perejra Nashsimentu Koshta Gonsalu
  • Perejra Muntejru Karlush Zhorzhe
  • Skaberle Fabio Antonio
  • Korrejya Alfar Soniya
  • Rejsh Di Abreu Artur Karlush
  • Migensh Perejra Mariya
  • Da Silva Arnaut Morejra Luish Gilerme
RU2712266C2
METHOD FOR PRODUCING CHLORINES AND PHARMACEUTICAL APPLICATIONS THEREOF 2009
  • Da Silva Arnaut Morejra Lujsh Gil'Ermi
  • Migensh Perejra Marija
  • Formozin'Ju Sanshesh Simojnsh Sebashtianu Zhoze
  • Magal'Jajnsh Simojnsh Serzhiu Paulu
  • Urbanska Kristina
  • Stokhel' Grazynja
RU2513483C2
LOW-MOLECULAR DERIVATIVES OF CARBOXAMIDE HALOGENATED PORPHYRINS, SPECIFICALLY CHLORINES AND BACTERIOCHLORINS, AND USE THEREOF 2016
  • Pereira Nascimento Costa Goncalo
  • Ferreira Goncalves Nuno Paulo
  • Pereira Monteiro Carlos Jorge
  • Reis De Abreu Artur Carlos
  • Ferraz Cardoso Soares Helder Tao
  • Borges Rocha Luis Gabriel
  • Schaberle Fabio Antonio
  • Miguens Pereira Maria
  • Da Silva Arnaut Moreira Luis Guilherme
RU2718923C2
CATALYST SYSTEM 2005
  • Istkhehm Grehkham
  • Tindehjl Nil
RU2372989C2
CATALYST SYSTEM 2003
  • Istkhehm Grehkham
  • Batler Ian
  • Fort'Jun Kevin
RU2326123C2
SUBSTITUTED ANILIDES, PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT 1998
  • Ehstlz Piter Charl'Z
  • Klark Dehvid Ehdvard
  • Kolliz Alan Dzhon
  • Koks Pol Dzhozef
  • Istvud Pol Dzhozef
  • Kharris Nejl Viktor
  • Laj Dzhastin Jeun Kvaj
  • Morli Ehndrju Dehvid
  • Porter Barri
RU2233269C2
CYCLOALKYLENE OR HETEROCYCLOALKYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITION, AEROSOL DEVICE, AND MEDICAL TREATMENT METHOD 1995
  • Ken D. Rajs
  • Dzheffri M. Dener
  • Ehntoni R. Gehngloff
  • Ehlajn I-Lin Kuo
RU2159229C2
HETEROCYCLIC COMPOUND 2017
  • Fujimoto, Jun
  • Liu, Xin
  • Kurasawa, Osamu
  • Takagi, Terufumi
  • Cary, Douglas Robert
  • Banno, Hiroshi
  • Asano, Yasutomi
  • Kojima, Takuto
RU2748693C2
HYDROQUINONE DERIVATIVES AS FREE OR SALT, METHODS OF THEIR SYNTHESIS, PIPERIDINE DERIVATIVES AND METHODS OF THEIR SYNTHESIS 1992
  • Gottfrid Sedel'Mejer[De]
  • Gerkhard Fisher[De]
RU2095339C1
METHODS FOR MODULATION OF FUNCTION OF SERINE/THREONINE-PROTEIN KINASE WITH 5-AZAQUINOXALINE-BASE COMPOUNDS, METHOD FOR IDENTIFICATION OF COMPOUNDS MODULATING FUNCTION OF SERINE/THREONINE-PROTEIN KINASE, METHOD FOR PROPHYLAXIS OR TREATMENT OF BODY PATHOLOGICAL STATE, 5-AZAQUINOXALINE-BASE PHARMACEUTICAL COMPOSITION AND METHOD FOR ITS SYNTHESIS 1998
  • Gjunter Ehkkhard
  • Kucher Berngard
  • Makmehjkhon Dzheral'D
  • Ehpp Garal'D
RU2223753C2

RU 2 399 622 C2

Authors

Migensh Perejra Marija

Arnaut Morejra Luish Gil'Ermi

Formozin'Ju Simojnsh Sebasht'Jan Zhoze

Montejro Karlush

Dates

2010-09-20Published

2005-11-10Filed