LAXATIVE SOLID DOSAGE FORM AND METHOD FOR PREPARING THEREOF (VERSIONS) Russian patent published in 2010 - IPC A61K31/4402 A61K47/00 A61K9/32 A61P1/10 

Abstract RU 2401106 C1

FIELD: medicine.

SUBSTANCE: solid dosage form consists of a core containing, wt %: bisacodyl - 1.5-12; potato starch - 0.5-10; pregelatinised starch - 2-15; croscarmellose sodium - 0.5-4; colloidal silicon dioxide - 0.2-5; stearic acid and/or its salts - 0.3-1.07; lactose - the rest; and a coating containing, wt %: polyethylene glycol - 0.05-0.2; staining agent - 0.05-0.25; titanium dioxide - 5-25; talc - 20-54; triethyl citrate - 1-7; colloidal silicon dioxide 0.5-2; sodium hydrocarbonate - 0.5-2; sodium lauryl sulphate - 0.1-1 and copolymer of methacrylic acid and ethyl acrylate - the rest.

EFFECT: invention ensures good strength and disintegration of a tablet in the neutral or alkalescent intestinal environment.

8 cl, 4 tbl

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RU 2 401 106 C1

Authors

Dates

2010-10-10Published

2009-04-09Filed