FIELD: medicine.
SUBSTANCE: solid dosage form consists of a core containing, wt %: bisacodyl - 1.5-12; potato starch - 0.5-10; pregelatinised starch - 2-15; croscarmellose sodium - 0.5-4; colloidal silicon dioxide - 0.2-5; stearic acid and/or its salts - 0.3-1.07; lactose - the rest; and a coating containing, wt %: polyethylene glycol - 0.05-0.2; staining agent - 0.05-0.25; titanium dioxide - 5-25; talc - 20-54; triethyl citrate - 1-7; colloidal silicon dioxide 0.5-2; sodium hydrocarbonate - 0.5-2; sodium lauryl sulphate - 0.1-1 and copolymer of methacrylic acid and ethyl acrylate - the rest.
EFFECT: invention ensures good strength and disintegration of a tablet in the neutral or alkalescent intestinal environment.
8 cl, 4 tbl
Authors
Dates
2010-10-10—Published
2009-04-09—Filed