FIELD: medicine, pharmaceutics.
SUBSTANCE: offered is a new modified release dosage form of trimetazidine dihydrochloride in the form of an oral tablet which contains an active substance in amount 3.5 - 70.0 wt %, mixed povidone and polyvinyl acetate as a release modifier in amount 20.0 - 70.0 wt % and pharmaceutically acceptable pharmaceutical aids. Preferentially, the dosage form of trimetazidine dihydrochloride as mixed povidone and polyvinyl acetate contains Collidon SR.
EFFECT: invention shall allow to enlarge the range of high quality, available domestic modified release drugs.
18 cl, 2 tbl
Authors
Dates
2011-02-27—Published
2009-10-08—Filed