FIELD: medicine.
SUBSTANCE: described is strain of hybrid cultivated cells of animals Mus. Musculus RIM9 - producer of monoclonal antibodies, specific to peptide of human milk - lactaptin and its recombinant analogues, which possess apoptotic activity with respect to human cancer cells. Invention allows to obtain monoclonal antibodies, recognising general linear antigen determinant of recombinant and natural lactaptin.
EFFECT: possibility to elaborate sensitive and specific test-systems for detecting lactaptin, antibodies to it and for isolation of lactaptin from human milk by method of affinity chromatography.
2 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| Mus Musculus ANIMAL HYBRID CULTURED CELL STRAIN PRODUCING benzo[a]pyrene AND benz[a]anthraccene SPECIFIC MONOCLONAL ANTIBODIES | 2010 |
|
RU2423519C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus MUSCULUS 1F1 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE NUCLEOCAPSID PROTEIN N OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2769817C1 |
| MUS MUSCULUS HYBRID CULTIVATED ANIMAL CELLS STRAIN α - THE PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO THE CANCER-TESTICULAR ANTIGEN OF THE PERSON GAGE | 2017 |
|
RU2652885C1 |
| STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS AS PRODUCER OF MONOCLONAL ANTIBODIES TO CONFORMATION-DEPENDENT DETERMINANTS OF TUMOR-ASSOCIATED HUMAN ANTIGEN MUC I | 2006 |
|
RU2319742C1 |
| STRAIN OF CULTURED ANIMAL HYBRID CELLS MUS. MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THE MEMBRANE PROTEIN COMMON TO TYPICAL AND ATYPICAL SEROGROUP 01 CHOLERA VIBRIOS | 2022 |
|
RU2785463C1 |
| STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS 2E1B5 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE RECEPROT-BINDING DOMAIN OF PROTEIN S OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2771288C1 |
| MUS MUSCULUS'S HYBRID CULTURE CELL STRAIN α PRODUCING MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR (GCSF) | 2013 |
|
RU2542381C2 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF MARBURG VIRUS, (Popp STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC SYSTEM FOR EXPOSING VP40 MATRIX PROTEIN OF MARBURG VIRUS (Popp STRAIN) | 2008 |
|
RU2395575C1 |
| HYBRID CELL STRAIN OF Mus. musculus ANIMALS - PRODUCER OF MONOCLONAL IVERMECTIN ANTIBODIES, AND MONOCLONAL IVERMECTIN ANTIBODIES | 2009 |
|
RU2415930C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus museums L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) | 2008 |
|
RU2395576C1 |
