AGENT FOR INCREASING RESERVED STEM CELL NUMBER IN ORGANISM Russian patent published in 2010 - IPC C12N5/00 C12N9/26 A61L2/14 A61K47/06 

Abstract RU 2405822 C1

FIELD: medicine.

SUBSTANCE: invention refers to radiation synthesis nanotechnology for the creation of a low-immunogenicity agent to increase the reserved stem cell number in an organism, and can be used in regenerative medicine. The agent represents polymer immobilised hyaluronidase introduced in the dissolved low-molecular water-soluble polymer pre-exposed to ionising radiation in dosage 1-5 Mrad, to final concentration 70 UN in 1 ml.

EFFECT: invention allows producing immobilised hyaluronidase which is characterised by substantially higher ability to increase the reserved stem cell number in an organism and effective both in parenteral, and in oral introduction.

4 tbl, 5 ex

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RU 2 405 822 C1

Authors

Artamonov Andrej Vladimirovich

Bekarev Andrej Aleksandrovich

Vereshchagin Evgenij Ivanovich

Dygaj Aleksandr Mikhajlovich

Zhdanov Vadim Vadimovich

Zjuz'Kov Gleb Nikolaevich

Udut Vladimir Vasil'Evich

Dates

2010-12-10Published

2009-03-05Filed