FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed is haemostimulating medicine, representing immobilised on polymer recombinant erythropoietin, characterised by the fact that recombinant erythropoietin is immobilised by electron-emitting impact by its introduction into solution of low-molecular water-soluble polymer (PEG, polyvinyl pyrrolidone, hydroxyethyl starch with molecular weight 400-4000 Da), preliminarily subjected to impact of ionising irradiation in dose 1-5 Mrad, to final concentration 500-5000 IU in 1 ml of solution. Shown is more expressed specific activity of medication in case of parenteral and per oral intake in comparison to medication "Mircera".
EFFECT: claimed medication does not possess immunogenic properties and does not demonstrate signs of allergenic action.
4 tbl
Title | Year | Author | Number |
---|---|---|---|
HEMOSTIMULANT AND EXCITANT AND METHOD FOR HEMOPOIESIS STIMULATION | 2009 |
|
RU2414926C1 |
AGENT FOR BODY GROWTH STIMULATION | 2011 |
|
RU2452509C1 |
AGENT INTENSIFYING ACTION OF BIOLOGICALLY ACTIVE SUBSTANCES AND DRUGS | 2009 |
|
RU2421239C1 |
AGENT FOR INCREASING RESERVED STEM CELL NUMBER IN ORGANISM | 2009 |
|
RU2405822C1 |
MEDICATION FOR REGENERATIVE MEDICINE | 2009 |
|
RU2406528C2 |
METHOD OF INCREASING STEM CELLS MOBILIZATION | 2009 |
|
RU2442601C2 |
DRUG POSSESSING REGENERATIVE ACTIVITY | 2011 |
|
RU2480236C1 |
METHOD FOR IMMOBILISING BIOLOGICALLY ACTIVE SUBSTANCE (BAS) ON CARRIER (VERSIONS) AND BAS-CARRIER CONJUGATE PRODUCED BY SUCH METHODS | 2008 |
|
RU2409669C9 |
HEPATOPROTECTOR | 2010 |
|
RU2444569C1 |
ERYTHROPOETIN CONJUGATED WITH POLYETHYLENE GLYCOL | 2010 |
|
RU2433134C1 |
Authors
Dates
2011-12-27—Published
2010-10-11—Filed