PREVENTIVE OR THERAPEUTIC AGENT FOR TREATMENT OF KERATOCONJUCTIVAL DISORDERS Russian patent published in 2010 - IPC A61K31/41 A61K31/95 A61P27/02 A61P27/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: there is offered an agent for treatment of dry eye syndrome, superficial punctuate keratopathy, corneal epithelium defect, corneal erosion, corneal ulcer, conjunctival epithelium defect, dry keratoconjunctiva, superior limbic keratoconjunctivitis, filamentous keratoconjunctivitis, keratitis or conjunctivitis, containing 2-phenyl-1,2-benzisoselenazol-3(2H)-one (ebselen) or its salts as an active ingredient, its administration and an appropriate therapy.

EFFECT: ebselen reduces corneal ageing in rats with extracted lachrymal gland better than physiologic saline and antioxidant alpha-lipoic acid.

9 cl, 2 tbl, 4 ex