FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of medicine, in particular, to ophthalmology. Therapeutic medication against keratoconjunctival disturbance is represented by compound of general formula 
, or its salt. In the given formula Y ring represents substituted or unsubstituted nitrogen-containing heterocyclic ring; R1 represents carboxy group or substituted or unsubstituted nitrogen-containing 5-member heterocyclic ring; Both R2 and R3 can be the same or different and represent hydrogen atom, substituted or unsubstituted alkyl group. In said formula X represents 
or 
.
EFFECT: invention ensures effect in treatment of keratoconjunctival disturbance, such as dry eyes, cornea ulcer, keratitis pr conjunctitis.
32 cl, 3 tbl, 8 ex
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