METHOD FOR STIMULATING NEOVASCULARISATION OF RETINA AND OPTIC NERVE IN RABBITS Russian patent published in 2010 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: stimulating neovascularisation of retina and optic nerve is ensured by the intravitreal introduction of an aqueous solution of recombinant human vascular endothelial growth factor in the amount 0.05-0.1 ml to experimental animals - rabbits. A dose of said agent is administered intermittently. On the 1st and 3rd days of experiment, the dose is 3 mcg, on the 7th and 11th days - 1.5 mcg, on the 15th day - 1.0 mcg, and on the 24th day - 5.0 mcg.

EFFECT: while being technically available and easily reproducible, the method provides the sequential development of eye grounds changes with a precise dependence from a dose administered that allows to follow all the stages of a pathological process leading to posterior eye vascularisation.

1 ex, 9 dwg