FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly to an antiangiogenic conjugate (embodiments). Said conjugate obtained by mixing peptide kv114* or Aib2 and oxidised hyaluronic acid with a molecular weight of 115–3000 kDa, contains in the structure one of the following fragments: 
or 
, wherein molar ratio of Aib2-HA is 1:60, and kv114*-HA is 1:170.
EFFECT: present invention provides conjugates of kv114* and Aib2 peptides with oxidised high-molecular hyaluronic acid with improved anti-angiogenic activity compared to free peptides.
2 cl, 15 dwg, 5 tbl, 1 ex
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