FIELD: medicine.
SUBSTANCE: method includes growing bacterium of Enterobacteriaceae family, which is modified by introduction of yeast gene ARO1 and extraction of aminoacid. Invention also relates to method for production of ester of lower alkyls of α-L-aspartyl-L-phenyl alanine, including growing specified bacterium, accumulation of L-phenyl alanine and synthesis of ester of lower alkyls of α-L-aspartyl-L-phenyl alanine from asparaginic acid or its derivatives and produced L-phenyl alanine.
EFFECT: invention makes it possible to produce aromatic amino acids and esters with high extent of efficiency.
12 cl, 2 dwg, 2 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF OBTAINING AROMATIC L-AMINO ACID USING Escherichia TYPE BACTERIA, IN WHICH ydiB GENE IS INACTIVATED, METHOD OF OBTAINING ESTER OF INFERIOR ALKYLS OF α -L-ASPARTYL-L-PHENYLALANINE | 2007 |
|
RU2355759C1 |
MUTANT PROTEIN, CODED BY GENE yddG, AND METHOD OF OBTAINING AROMATIC L-AMINO ACIDS WITH APPLICATION OF BACTERIA OF GENUS Escherichia | 2012 |
|
RU2530171C2 |
METHOD FOR PREPARING L-AMINO ACIDS BY USING MICROORGANISMS POSSESSING ENHANCED EXPRESSION OF pckA GENE | 2003 |
|
RU2268300C2 |
METHOD FOR PREPARING L-THREONINE USING MICROORGANISM BELONGING TO ESCHERICHIA GENUS WHEREIN hipA GENE IS INACTIVATED | 2005 |
|
RU2320718C2 |
METHOD FOR PRODUCTION OF L-AMINO ACIDS BY FERMENTATION USING BACTERIA HAVING INCREASED EXPRESSION OF XYLOSE UTILIZATION GENE | 2005 |
|
RU2283346C1 |
6-PHOSPHOGLUCONOLACTONASE FROM ESCHERICHIA COLI, DNA FRAGMENT, MICROORGANISM BELONGING TO ESCHERICHIA GENUS AS PRODUCER OF L-AMINO ACID AND METHOD FOR PREPARING L-AMINO ACIDS | 2005 |
|
RU2288268C2 |
METHOD FOR PREPARING L-AMINO ACIDS USING MICROORGANISM BELONGING TO GENUS ESCHERICHIA | 2005 |
|
RU2311454C2 |
METHOD OF OBTAINING L-THREONINE OR L-ARGININE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH GENE fdrA IS INACTIVATED | 2006 |
|
RU2337957C2 |
BACTERIUM OF Escherichia GENUS WITH INACTIVATED pnp GENE PRODUCING L-THREONINE AND L-THREONINE TECHNIQUE | 2005 |
|
RU2330883C2 |
METHOD FOR PREPARING L-AMINO ACIDS USING MICROORGANISM BELONGING TO GENUS Escherichia WHEREIN leuO GENE IS INACTIVATED | 2006 |
|
RU2312894C1 |
Authors
Dates
2011-01-10—Published
2008-06-17—Filed