FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmacology and represents a pharmaceutical composition with high stability and solubility, made of 1 weight part of orlistat as pharmacologically active substance, poorly soluble and with low melting point, from 0.01 to 20 weight parts of dissolvent, from 0.01 to 20 weight parts of solubiliser, from 0.01 to 10 weight parts of surfactant, from 0.01 to 2 weight parts of antioxidant and from 0.1 to 20 weight parts of adsorbent or dispergator, at the same time level of pH stabilisation is from 4.5 to 5.5.
EFFECT: invention provides for solution of problems arising as a result of low melting temperature and possible decay under storage conditions and improved solubility.
7 cl, 11 ex, 4 tbl
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Authors
Dates
2011-01-20—Published
2006-06-26—Filed