PHARMACEUTICAL COMPOSITION WITH HIGH STABILITY AND SOLUBILITY AND PRODUCTION PROCESS Russian patent published in 2011 - IPC A61K31/365 

Abstract RU 2409362 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmacology and represents a pharmaceutical composition with high stability and solubility, made of 1 weight part of orlistat as pharmacologically active substance, poorly soluble and with low melting point, from 0.01 to 20 weight parts of dissolvent, from 0.01 to 20 weight parts of solubiliser, from 0.01 to 10 weight parts of surfactant, from 0.01 to 2 weight parts of antioxidant and from 0.1 to 20 weight parts of adsorbent or dispergator, at the same time level of pH stabilisation is from 4.5 to 5.5.

EFFECT: invention provides for solution of problems arising as a result of low melting temperature and possible decay under storage conditions and improved solubility.

7 cl, 11 ex, 4 tbl

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RU 2 409 362 C2

Authors

Moon Zhoo Mjung

Lee Khjun Akh

Dates

2011-01-20Published

2006-06-26Filed