RNAI-MODULATION OF RSV, PIV AND OTHER RESPIRATORY VIRUSES AND APPLICATION THEREOF Russian patent published in 2011 - IPC C12N7/00 

Abstract RU 2409666 C2

FIELD: medicine.

SUBSTANCE: method of decreasing the levels of protein, mRNA or titre of respiratory syncytial virus (RSV) in an airway cell provides the introduction of a siRNA agent. The siRNA agent contains a sense chain 15-23 nucleotides long and a complementary anti-sense chain 15-23 nucleotides long. The siRNA agent is introduced by inhalation or intranasal spraying. There is also presented a method of decreasing the levels of titre of respiratory syncytial virus (RSV) and parainfluenza virus (PIV). Also, the method provides combined introduction of two siRNA agent.

EFFECT: inventions can be used in medicine.

16 cl, 5 dwg, 1 tbl

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RU 2 409 666 C2

Authors

Barik Sajlen

Dates

2011-01-20Published

2005-10-21Filed