FIELD: medicine.
SUBSTANCE: method of decreasing the levels of protein, mRNA or titre of respiratory syncytial virus (RSV) in an airway cell provides the introduction of a siRNA agent. The siRNA agent contains a sense chain 15-23 nucleotides long and a complementary anti-sense chain 15-23 nucleotides long. The siRNA agent is introduced by inhalation or intranasal spraying. There is also presented a method of decreasing the levels of titre of respiratory syncytial virus (RSV) and parainfluenza virus (PIV). Also, the method provides combined introduction of two siRNA agent.
EFFECT: inventions can be used in medicine.
16 cl, 5 dwg, 1 tbl
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Authors
Dates
2011-01-20—Published
2005-10-21—Filed