IRNA AGENT FOR REDUCING LEVELS OF VIRAL PROTEIN, IRNA OR RESPIRATORY SYNCYTIAL VIRUS TITRE IN RESPIRATORY CELL Russian patent published in 2013 - IPC A61K31/7088 A61P11/00 

Abstract RU 2494745 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology, and concerns an iRNA agent for reducing the levels of viral protein, iRNA, or respiratory syncytial virus titre in an individual's respiratory cell. The present iRNA agent contains a sense chain and an antisense chain, wherein the above sense chain comprises at least 15 consecutive nucleotides complementary to the gene P of the RSV virus, and the antisense chain comprises at least 15 consecutive nucleotides complementary to said sense chain, wherein said antisense chain comprises 15 or more consecutive nucleotides of a sequence consisting of nucleotides 1-19 of the sequence SEQ ID NO:6.

EFFECT: invention may be used in treating the respiratory diseases and preparing the RSV vaccines.

8 cl, 5 dwg, 1 tbl

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RU 2 494 745 C2

Authors

Barik Sajlen

Dates

2013-10-10Published

2005-10-21Filed