FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology, and concerns an iRNA agent for reducing the levels of viral protein, iRNA, or respiratory syncytial virus titre in an individual's respiratory cell. The present iRNA agent contains a sense chain and an antisense chain, wherein the above sense chain comprises at least 15 consecutive nucleotides complementary to the gene P of the RSV virus, and the antisense chain comprises at least 15 consecutive nucleotides complementary to said sense chain, wherein said antisense chain comprises 15 or more consecutive nucleotides of a sequence consisting of nucleotides 1-19 of the sequence SEQ ID NO:6.
EFFECT: invention may be used in treating the respiratory diseases and preparing the RSV vaccines.
8 cl, 5 dwg, 1 tbl
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Authors
Dates
2013-10-10—Published
2005-10-21—Filed