FIELD: medicine.
SUBSTANCE: by means of bioluminescent method determined is activity of NADPH- and NADP-dependent reactions of glutamatdehydrogenases of peripheral blood lymphocytes of patients with chronic hepatitis C, and value of coefficient NADPH/NADP+ in enzymatic reactions of glutamatdehydrogenase is used to make conclusion about possibility to develop chronic hepatitis C exarcerbation. If coefficient value is ≥25, development of exarcerbation is predicted, if coefficient value is <25 - absence of exarcerbation.
EFFECT: application of method allows to make quick prediction of CHC exacerbation in children with clinical-biochemical remission at early stages.
1 tbl, 4 ex
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Authors
Dates
2011-02-20—Published
2009-08-05—Filed