DRUG FOR TREATMENT OF ANEMIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE AND METHOD FOR ITS OBTAINING Russian patent published in 2021 - IPC A61K9/20 A61K31/472 A61K47/26 A61K47/36 A61K47/38 A61K47/58 A61P7/08 

Abstract RU 2749719 C1

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of medicine, namely to internal medicine and pharmacology, and is intended for the treatment of anemia. The drug for the treatment of anemia associated with chronic kidney disease, in the form of a tablet, consists of a core, including roxadustat and excipients, and a film shell. As auxiliary substances, the core contains lactose monohydrate, Comprecel, croscarmellose sodium, starch, colloidal anhydrous silicon dioxide, Kollidon 25 and pharmaceutically acceptable salts of stearic acid. AquaPolish®P is used as a film casing. Components are used in the stated quantities. According to another embodiment, a method for preparing the drug is provided.

EFFECT: use of a group of inventions makes it possible to increase the uniformity and stability of the dosage form, improve the technological characteristics for its preparation, and also optimize the release profile of roxadustat.

4 cl, 2 tbl, 4 ex

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RU 2 749 719 C1

Authors

Balabanyan Vadim Yurevich

Fazylov Marat Feliksovich

Dates

2021-06-16Published

2020-10-08Filed