N-FORMYL HYDROXYAMINE DERIVATIVES Russian patent published in 2011 - IPC C07D401/12 C07D403/12 A61K31/4025 

Abstract RU 2412939 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula (I) where: R1 denotes C1-C10alkyl, C3-C10cycloalkyl; R3 denotes H, halide; R4 denotes a 6-member monocyclic heteroaryl containing 1-2 nitrogen atoms, one of which can be oxidised, optionally substituted with a halide; n ranges from 0 to 3; provided that R1 denotes C3-C10cycloalkyl and/or R4 denotes a 6-member monocyclic heteroaryl optionally substituted with a halide and containing 2 ring N heteroatoms, one of which can be oxidised or pharmaceutically acceptable salt thereof.

EFFECT: obtaining peptidyl deformylase (PDF) inhibiting compounds.

12 cl, 24 ex

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RU 2 412 939 C2

Authors

Braken Katrin Rine

Bashell Sajmon

Din Karl

Frankavilla Charlz

Dzhejn Rakesh K.

Li Kvankho

Sipersaud Mokhindra

Shu Lehj

Sundaram Aratia

Juan' Chzhehn'Gju

Dates

2011-02-27Published

2006-05-22Filed