FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to bioadhesive carrier for mucous membranes with delayed release of active component. Carrier contains primary granules, which include active component, 1-75 wt % of diluting agent 1-10 wt % of alkyl sulfate of alkaline metal and 0.5-5 wt % of binding substance, as well as 5-80 wt % of bioadhesive polymer, selected from group including natural polymers, said natural polymers represent polysaccharides, natural proteins of animal or vegetable origin, or synthetic polymers and 5-80 wt % of polymer, ensuring delayed release of active component, carrier does not contain lactose and corn starch. Said carrier ensures delivery of active component during long period, constituting more than 20 hours.
EFFECT: invention relates to method of obtaining bioadhesive carrier and to its application for treatment of mucous membrane diseases.
33 cl, 7 dwg, 2 tbl, 13 ex
Title |
Year |
Author |
Number |
PHARMACEUTICAL COMPOSITION CONTAINING ELECTROHYDRODYNAMICALLY PRODUCED FIBERS, COMPOSITION HAVING IMPROVED RETENTION TIME AT SITE OF USE |
2016 |
- Hansen, Jens
- Romero, Martin Eduardo Santocildes
|
RU2701513C2 |
COMPOSITIONS COMPRISING ELECTROHYDRODYNAMICALLY PRODUCED FIBERS FOR APPLYING GIVEN DOSES OF THE ACTIVE SUBSTANCE TO THE SKIN OR MUCOSA |
2015 |
- Hansen, Jens
- Christiansen, Lars Hellerung
|
RU2695217C2 |
IMPROVEMENT OF COMPOSITIONS OR WHATEVER IS RELEVANT TO COMPOSITIONS |
2009 |
|
RU2493829C2 |
LIQUID DRUG RESERVOIRS |
2005 |
- Turesson Krister
- Tiberg Fredrik
- Jokhansson Markus
- Kharvigsson Ian
- Joabsson Fredrik
- Jokhnsson Markus
|
RU2390331C2 |
DRUG FOR HUMAN PAPILLOMA VIRUS ASSOCIATED DISEASES OF UTERINE NECK, PRESENTED IN FORM OF SOLUTION FOR VAGINAL IRRIGATIONS, KIT AND METHOD FOR PREPARING |
2010 |
- Pavlova Ljudmila Anatol'Evna
- Ul'Janov Andrej Mikhajlovich
- Kiselev Vsevolod Ivanovich
|
RU2438652C1 |
COMPOSITIONS FOR DELIVERY OF SUBSTANCES FOR ORAL CAVITY CARE, WHICH CONTAIN SILICONE PRESSURE-SENSITIVE ADHESIVES |
2007 |
- Gosh Chanchal Kumar
- Madzheti Satianarajana
- Kovaks Stefen Andras
|
RU2433815C2 |
PARTICLES FOR ACTIVE INGREDIENT DELIVERY, METHOD FOR MAKING THEREOF AND BASED COMPOSITIONS |
2007 |
- Singkh Amardzhit
- Singkh Sarabdzhit
- Singkh Paramdzhit
- Dzhain Radzhesh
|
RU2413506C2 |
POLYETHYLENE GLYCOL COMPOSITIONS FOR CONTROL OF RELAPSES OF LABIAL HERPES, GENITAL HERPES AND HERPES ZOSTER |
2011 |
- Vitins Peter
- Langenauer Marsel
- Sherer Pol Martin
|
RU2643763C2 |
BIOADHESIVE LIQUID COMPOSITION, ESSENTIALLY WATER-FREE |
2004 |
- Richardson Dzhonatan Krejg
- Melia Kolin Dehvid
- Dettmar Piter Uill'Jam
- Khampson Frehnk Chaduik
- Dzholliff Iehn Gordon
|
RU2336092C2 |
PHARMACEUTICAL COMPOSITION ELICITING ANTIVIRAL ACTIVITY AND METHOD OF ITS PREPARING |
2001 |
|
RU2175230C1 |