BIOADHESIVE CARRIER WITH DELAYED RELEASE FOR MUCOUS MEMBRANES, INTENDED FOR DELIVERY OF ACTIVE COMPONENTS Russian patent published in 2011 - IPC A61K9/22 A61K45/08 A61K31/522 A61K31/4468 A61K31/4178 A61K47/04 A61K47/30 A61K47/36 A61K47/42 A61P31/12 A61J3/10 

Abstract RU 2420267 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to bioadhesive carrier for mucous membranes with delayed release of active component. Carrier contains primary granules, which include active component, 1-75 wt % of diluting agent 1-10 wt % of alkyl sulfate of alkaline metal and 0.5-5 wt % of binding substance, as well as 5-80 wt % of bioadhesive polymer, selected from group including natural polymers, said natural polymers represent polysaccharides, natural proteins of animal or vegetable origin, or synthetic polymers and 5-80 wt % of polymer, ensuring delayed release of active component, carrier does not contain lactose and corn starch. Said carrier ensures delivery of active component during long period, constituting more than 20 hours.

EFFECT: invention relates to method of obtaining bioadhesive carrier and to its application for treatment of mucous membrane diseases.

33 cl, 7 dwg, 2 tbl, 13 ex

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RU 2 420 267 C2

Authors

Kostantini Dominike

Lemarchand Karolina

Dates

2011-06-10Published

2007-03-23Filed