PREVENTIVE OR THERAPEUTIC AGENT FOR DEPRESSION OR ANXIETY DISORDER Russian patent published in 2011 - IPC A61K31/343 A61K45/00 A61K31/554 A61K31/4525 A61P25/24 

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are offered: the use of (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide (Ramelteon) in combination with one or more drug substances chosen from fluoxetine, sertraline, paroxetine, mianserine, milnacyprane, cytalopram, escytalopram, fluvoxamine, minaprine, duloxetine, venlafaxine, imipramine, clomipramine, doxepine, trazodone, nephazodone, amitriptyline, carbamazepine, mirtazapine, diazepam, flutazolam, lorazepam, buspirone, tandospirone, ethyl loflazepat, flutoprazepam, mexazolam, clothiazepam, ethizolam, hydroxysine, alprazolam, fludiazepam, chlorodiazepoxide, cloxazolam, clorazepat and oxazolam for making a pharmaceutical composition for prevention or treatment of depression or anxiety disorder, for prevention or treatment of depression or anxiety disorder in the patients with underlying diabetes, hyperlipidemia, hypertension or metabolic syndrome, as well as appropriate methods of treating.

EFFECT: intensified effect of diazepam or paroxetine in joint administration with Ramelteon with no adverse reactions.

4 cl, 14 dwg, 1 tbl, 5 ex