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2 394 034

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IPC

C07D471/04(2006-01-01)

C07D213/18(2006-01-01)

A61K31/4162(2006-01-01)

A61P25/24(2006-01-01)

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Application

2007115741/04, 2007-04-26

(24)

Start date

2007-04-26

(22)

Actual filing date

2007-04-26

(45)

Published

2010-07-10

(72)

Inventor

Seredenin Sergej BorisovichVoronina Tat'Jana AleksandrovnaGlozman Oleg MikhajlovichZhmurenko Ljudmila AleksandrovnaMolodavkin Gennadij MatveevichMeletova Ol'Ga Konstantinovna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Farmakologii Imeni V.V. Zakusova Ramn

DERIVATIVES OF 4,6-DIMETHYL-2,3-DIHYDRO-1H-PYRAZOLO[4,3-c] PYRIDINE-3-ONES AND ETHERS 2,6-DIMETHYL-4-PHENYL-HYDRAZINE NICOTINIC ACIDS AS INTERMEDIATE PRODUCTS FOR THEIR SYNTHESIS, POSSESSING ANTIDEPRESSANT AND ANXIOLYTIC POTENCY Russian patent published in 2010 - IPC C07D471/04 C07D213/18 A61K31/4162 A61P25/24

Abstract RU 2394034 C2

FIELD: medicine.

SUBSTANCE: invention refers to compounds having anxiolytic and antidepressant activity, which are derivatives of the formula 1 (a-b), or formula 2 (a-b) at that compounds of formula 2 (a-b) are intermediate products in synthesis of compounds of the formula , where R-Cl is a compound 1a or R'=COOC₂H₅ - compound 1b, , where R=COOC₂H₅ and R'=C1 - compound 2a; R=R-COOC₂H₅ - compound 2b.

EFFECT: obtaining new biologically active compounds that differ from analogues as intended in low toxicity and lack of side effects.

5 cl, 3 ex, 5 tbl

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RU 2 394 034 C2

Authors

Seredenin Sergej Borisovich

Voronina Tat'Jana Aleksandrovna

Glozman Oleg Mikhajlovich

Zhmurenko Ljudmila Aleksandrovna

Molodavkin Gennadij Matveevich

Meletova Ol'Ga Konstantinovna

Dates

2010-07-10—Published

2007-04-26—Filed