GABA-STEROID ANTAGONISTS AND APPLICATION THEREOF IN TREATING CNS DISTURBANCES Russian patent published in 2011 - IPC A61K31/56 A61P25/28 

Abstract RU 2413516 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present group of inventions refers to medicine, namely to psychiatry, and concerns the use of GABA-steroid antagonists for treating central nervous system disturbances. That is ensured by administration of compounds of the group of GABA-steroid antagonists exhibiting blocking action in relation to 3alpha-hydroxy-5alpha/beta-steroids practically without an antagonist effect on a receptor A of gamma-aminobutyric acid (GABA), and compounds having selective antagonist effect on said receptor.

EFFECT: invention provides treatment and/or prevention of CNS disturbances caused by action of 3alpha-hydroxy-5alpha/beta-steroid, as well as GABA-A overstimulation.

9 cl, 4 tbl, 2 dwg, 2 ex

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RU 2 413 516 C2

Authors

Behkstrem Torb'Orn

Lundgren Pehr

Vang Ming-De

Dates

2011-03-10Published

2005-11-07Filed