GLUCURONIDATED NEBIVOLOL METABOLITES Russian patent published in 2011 - IPC A61K31/70 A61K31/35 A61P9/00 

Abstract RU 2413518 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: given invention refers to pharmacology and concerns a pharmaceutical composition for increasing nitrogen oxide release from human endotheliocytes, containing at least one diastereoisomer of glucuronidated nebivolol metabolite of formula as well as to a standard dosage form containing at least at least one diastereoisomer of glucuronidated nebivolol metabolite of formula 1.

EFFECT: invention provides effective nitrogen oxide release and facilitated washout of nebivolol metabolites.

2 cl, 5 dwg, 4 tbl, 1 ex

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RU 2 413 518 C2

Authors

O'Donnell Dzhon P.

Ouehns Uolter

Dankan Dzhozef

Sho Ehndrju

Dates

2011-03-10Published

2006-01-30Filed