FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmacology and represents a method for making pancreatine including heating of a dispersed form of pancreatine containing one or more solvents at temperature at least 85°C for 48 h to ensure total concentration of solvents in the dispersed form of pancreatine equal or less than 3.5 wt % at any moment of said heating process, while the dispersed form of pancreatine is specified from powder, pellets, micropellets, microspheres, granules and granulates.
EFFECT: invention provides lower content of biologically active impurities in pancreatine and maintained enzymatic activity of lipase, protease and amylase at an acceptable level by 50 % and more from the initial enzymatic activity.
32 cl, 22 ex, 7 tbl, 5 dwg
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