FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to novel substituted imidazole compounds of formula I 
where values of radicals are given in description, as well as to their based on them pharmaceutical compositions.
EFFECT: formula I compounds, as well as their salts, esters and compositions based on them possess ability to inhibit protein of kinesin spindle (KSP) and can be used for treatment of cancer diseases.
40 cl, 15 ex, 3 tbl
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