FIELD: medicine.
SUBSTANCE: invention relates to binder-active compound conjugates (ADC), where the molecule of the active compound is a spindle kinesin protein inhibitor bound to the binder through the linker, wherein the binder is an antibody or its antigen-binding fragment. Also disclosed are methods of producing said ADC.
EFFECT: conjugates are intended for preparing a drug for treating and/or preventing diseases, such as hyperproliferative and/or angiogenic diseases.
75 cl, 7 dwg, 40 tbl, 256 ex
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