INDOLE-3-CARBONYL-SPIRO-PIPERADINE DERIVATIVES AS V1a RECEPTOR ANTAGONISTS Russian patent published in 2011 - IPC C07D401/06 C07D471/10 C07D491/10 A61K31/454 A61P9/00 

Abstract RU 2414466 C2

FIELD: chemistry.

SUBSTANCE: invention relates to indol-3-yl-carbonyl-spiro-piperadine derivatives used as V1a receptor antagonists and which have formula I: , where the spiro-piperadine A head group and residues R1, R2 and R3 are as defined in claim 1 of the invention. The invention also pertains to pharmaceutical compositions which contain such compounds and use thereof in preparing medicines with V1a receptor antagonist activity.

EFFECT: high activity of derivatives.

37 cl, 1 tbl, 285 ex

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Authors

Bissants Katerina

Grundshober Kristof

Ratni Khasan

Rodzhers-Ehvans Mark

Shnajder Patrik

Dates

2011-03-20Published

2006-07-04Filed