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(19)

(11)

2 420 529

(13)

(51)

IPC

C07D471/10(2006-01-01)

C07D498/10(2006-01-01)

A61K31/438(2006-01-01)

A61P9/02(2006-01-01)

(21) (22)

Application

2008125813/04, 2006-12-19

(24)

Start date

2006-12-19

(22)

Actual filing date

2006-12-19

(45)

Published

2011-06-10

(72)

Inventor

Bissants KaterinaGrundshober KristofRatni KhasanRodzhers-Ehvans MarkShnajder Patrik

(73)

Holder

F. Khoffmann-Lja Rosh Ag

INDOLE-3-YL-CARBONYL-SPIRO-PIPERIDINE DERIVATIVES Russian patent published in 2011 - IPC C07D471/10 C07D498/10 A61K31/438 A61P9/02

Abstract RU 2420529 C2

FIELD: medicine.

SUBSTANCE: invention refers to indole-3-yl-carbonyl-spiro-piperidine derivatives which have an effect of Vla-receptor antagonists and are presented by Formula I: where a tail spiropiperidine group A and residual R¹, R² and R³ are such as specified in the patent claim.

EFFECT: higher efficiency of applying the compounds in drugs effective in dysmenorrhea, hypertension, chronic heart failure, inadequate vasopressin secretion, hepatic cirrhosis, nephrotic syndrome, obsessive-compulsive disorder, anxious and depressive disorders.

22 cl, 42 ex

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RU 2 420 529 C2

Authors

Bissants Katerina

Grundshober Kristof

Ratni Khasan

Rodzhers-Ehvans Mark

Shnajder Patrik

Dates

2011-06-10—Published

2006-12-19—Filed