PHOSPHORAMIDATE ALKYLATOR PRODRUG Russian patent published in 2011 - IPC C07F9/24 A61K31/664 A61P35/00 

Abstract RU 2414475 C2

FIELD: chemistry.

SUBSTANCE: invention relates to phosphoramidate alkylator prodrugs which can be used to treat cancer separately or combined with other anti-tumour agents, having formula: , where each X4 denotes Cl or Br.

EFFECT: obtaining novel compounds, having antiproliferative activity and pharmaceutical compositions based on said compositions.

9 cl, 7 dwg, 56 ex, 43 tbl

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RU 2 414 475 C2

Authors

Matteuchchi Mark

Duan' Tszjan'-Sin'

Tszjao Khajlun

Kajzerman Dzhekob

Ammons Stiv

Dates

2011-03-20Published

2006-06-29Filed