METHOD OF OBTAINING MEDICATION, WHICH HAS TISSUE-SPECIFIC ACTIVITY, AND MEDICATION, OBTAINED BY CLAIMED METHOD (VERSIONS) Russian patent published in 2011 - IPC A61K35/28 A61K35/34 A61K35/38 A61K35/39 A61K35/55 A61P43/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to pharmacology and medicine. Fin order to obtain medicine, which has tissue-specific activity, animal organs are subjected to freezing not later than after 2 hours after raw material collection at temperature not lower than 40°C, kept at temperature minus 20-22°C during not less than two months. To milled frozen raw material 5% solution of acetic acid is added, bringing suspension temperature to 60-70°C and extraction of peptides into solution is carried out with constant mixing during not less than 2 hours. Supernatant fluid is siphoned and filtered through tissue, after which purified extract is directed to tangential micro-filtering. Obtained filtrate is directed to solid-phase extraction. Chromatography is carried out and on output from columns fractions of solutions are collected. Fractions, which contain peptide components, are united and directed to vacuum-evaporating plant, after which obtained target product is lyophilised.

EFFECT: method application makes it possible to obtain peptide complex with molecular weight of peptide components included in it from 75 to 5200 Da, which demonstrates pronounced tissue-specific activity.

8 cl, 14 tbl, 14 ex