METHOD OF PRODUCING CARBAMIDE, LABELLED WITH STABLE C ISOTOPE Russian patent published in 2011 - IPC C07C273/04 C07C275/04 C07C275/06 C07B59/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a novel method of producing carbamide with a stable ¹³C isotope used in medical diagnostics, involving reaction of labelled carbon dioxide and ethylene oxide at temperature 80-150°C, pressure 2.1-6 MPa in the presence of a catalyst - complex of zinc bromide and tertiary organophosphines in molar ratio of ethylene oxide to the catalyst equal to 500-5000:1, followed by extraction of the labelled ethylene carbonate and ammonolysis of the extracted ethylene carbonate at temperature 120-170°C and pressure 2.8-4.7 MPa.

EFFECT: possibility of obtaining an end product with good output using a fairly simple and technologically effective method.

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