FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel isoxazolines and isoxazoles of the formula (I) 
where R1,R14,R15, U, V, W, X, Y and b have values given in the invention claim. Compounds are useful as antagonists of glycoprotein fibrinogen receptors IIb/IIIa of platelets. Invention relates to also pharmaceutical compositions containing these compounds, method of inhibition of platelet aggregation based on these compounds as thrombolytic agents. EFFECT: improved method of inhibition. 24 cl, 16 tbl, 2423 ex
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