FIELD: medicine, experimental pharmacology.
SUBSTANCE: the present innovation should be applied in manufacturing medicinal preparations that correct immune and hepatobiliary body systems. The innovation deals with the method to obtain liposomes being of immunocorrecting and hepatoprotector action: one should carry out extraction of phospholipids out of Baikal seal's liver, dissolve the mixture of the obtained phospholipids and Baikal seal's fat in organic solvent at the ratio of 4:6 with α-tocopherol antioxidant, dry a thin layer of lipids upon a rotor evaporator, add buffer solution, shake the mixture to obtain homogeneous suspension, process the lipid mixture with ultrasound at water cooling, then the mixture should be centrifuged to separate the upper three fourths of supernatant. The declared method enables to obtain liposomal preparation being of independent curative-immunocorrecting and hepatoprotector action and broaden raw materials source to obtain liposomes due to applying cheap natural raw material.
EFFECT: higher efficiency.
6 tbl
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Authors
Dates
2007-10-27—Published
2006-05-16—Filed