NEW CRYSTALLINE FORMS OF TIOTROPIUM BROMIDE Russian patent published in 2011 - IPC C07D451/10 A61K31/46 A61P11/06 

Abstract RU 2417224 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to crystalline tiotropium bromide anhydrate differing in X-ray diffraction values by the presence of an orthorhombic elementary cell with the parameters a=11.7420 (4) Å, b=17.7960 (7) Å, c=19.6280 (11) Å and the cell volume V=4101.5 (3) Å.

EFFECT: invention refers to method for preparing said form of tiotropium bromide and to a based pharmaceutical composition for treating respiratory diseases, first of all for treating chronic obstructive pulmonary disease and asthma.

5 cl, 15 dwg, 18 tbl, 15 ex

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RU 2 417 224 C2

Authors

Pop Mikhaehla-Marija

Mjul'Der-Udajer Stefani

Lamkadmi Mimoun

Dates

2011-04-27Published

2006-04-21Filed