FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of medicine and pharmacy, namely to tablet of prolonged release, which consists of, at least, two layers, and is different due to the fact that, at least, one layer quickly releases medication 1S,9S(RS,3S)N-(2-ethoxy-5-oxo-tetrafuran-3-yl)-6,10-dioxo-9-(isoquinolen-1-oyl-amino)-1,2,3,4,7,8,9,10-octahydro-6-H-pyridazino[1,2-a][1,2]diazepine-1-carboxamide and, at least one layer releases in delayed manner medication 1S,9S(RS,3S)N-(2- ethoxy -5-oxo-tetrafuran-3-yl)-6,10-dioxo-9-( isoquinolen-1-oyl-amino)-1,2,3,4,7,8,9,10-octahydro -6-H- pyridazino [ 1,2-a] [1,2] diazepine-1 - carboxamide for treatment of autoimmune diseases, type I and type II diabetes, rheumatoid arthritis, osteoarthritis and/or psoriasis.
EFFECT: obtaining tablet with prolonged release.
8 cl, 2 dwg, 1 ex
Title | Year | Author | Number |
---|---|---|---|
DRUG OF SUSTAINED-RELEASE ACTIVE SUBSTANCE | 1994 |
|
RU2138253C1 |
SOLID ENTERIC ORAL DOSAGE FORM OF PROINSULIN C-PEPTIDE (VERSIONS) AND METHOD FOR PREPARING IT (VERSIONS) | 2013 |
|
RU2522897C1 |
TRIMETAZIDINE PREPARATION AS MATRIX TABLET OF PROLONGED ACTION AND METHOD FOR MAKING THEREOF | 2007 |
|
RU2377989C2 |
CONTROLLED RELEASE TRIMETAZIDINE MATRIX TABLET | 2006 |
|
RU2367438C2 |
METHOD OF OBTAINING MEDICAL FORM OF TRIMETAZIDINE OF PROLONGED ACTION | 2012 |
|
RU2530558C2 |
BI-LAYER TABLET COMPOSITION | 2010 |
|
RU2583920C2 |
TWO-LAYER TABLET COMPOSITION | 2020 |
|
RU2824129C2 |
TAMZULOSIN TABLETS | 2002 |
|
RU2311903C2 |
DOUBLE-LAYER TABLET COMPOSITION | 2010 |
|
RU2712757C2 |
DOSAGE FORMS CONTAINING DOPAMINE AGONISTS FOR PARENTERAL ADMINISTRATION | 2009 |
|
RU2532347C2 |
Authors
Dates
2011-05-27—Published
2006-09-29—Filed