FIELD: chemistry; medicine.
SUBSTANCE: invention relates to compositions of a two-layer tablet containing a sustained release (XR) composition of metformin or a reduced weight metformin composition as a first layer, an SGLT2 inhibitor composition as a second layer and optionally a film coating.
EFFECT: present invention provides methods of producing a two-layer tablet composition and methods of treating diseases and disorders associated with SGLT2 activity using the two-layer tablet compositions.
6 cl, 2 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BI-LAYER TABLET COMPOSITION | 2010 |
|
RU2583920C2 |
| DOUBLE-LAYER TABLET COMPOSITION | 2010 |
|
RU2712757C2 |
| COMPOSITIONS OF PILL WITH IMMEDIATE RELEASE | 2010 |
|
RU2558798C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING AMINO COMPOUND | 2012 |
|
RU2607480C2 |
| COMPOSITIONS OF METFORMIN WITH REDUCED WEIGHT | 2010 |
|
RU2564901C2 |
| PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITOR OF HMG-REDUCTASE | 2000 |
|
RU2206324C1 |
| PHARMACEUTICAL COMBINATION, COMPOSITION, AND COMBINED FORMULATION CONTAINING A GLUCOKINASE ACTIVATOR AND AN SGLT-2 INHIBITOR, AND METHODS FOR PRODUCTION AND APPLICATION THEREOF | 2019 |
|
RU2770043C1 |
| PHARMACEUTICAL COMBINATION, COMPOSITION, AND COMBINED COMPOSITION CONTAINING GLUCOKINASE ACTIVATOR AND BIGUANIDE HYPOGLYCEMIC DRUG, AS WELL AS THEIR PREPARATION METHOD, AND THEIR USE | 2019 |
|
RU2780377C2 |
| COMBINED COMPOSITION CONTAINING METFORMIN OF SUSTAINED RELEASE AND INHIBITOR HMG-CoA-REDUCTASE OF IMMEDIATE RELEASE | 2014 |
|
RU2651460C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING DORAVIRINE, TENOFOVIR DISOPROXIL FUMARATE AND LAMIVUDINE | 2016 |
|
RU2736941C2 |
