HETEROCYCLIC COMPOUNDS EFFECTIVE AS ANABOLIC AGENTS FOR CATTLE Russian patent published in 2011 - IPC C07D487/06 A61K31/55 A61P3/00 A61P43/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a compound of formula

, or its pharmaceutically and veterinary acceptable salts, where: A represents -CH₂-; and B represents -CH₂-, -C(CH₃)₂-; or -A-B- represents -CH=CH-; one of R¹ and R² represents CH₃ and another represents H; R³, R⁴, R⁵, R⁶ and R⁷, each is independently selected from H, R⁸ and R⁹; or R⁴ and R⁵ together represent -OCH₂-CH₂-, -CH₂-CH₂-O- or -O-CH₂-O- and R³, R⁶ and R⁷, each represents H; R⁸ represents halogen, -CN, C₁-C₄alkyl, C₁-C₄haloalkyl, -CH₂OH, -O-(C₁-C₄ alkyl), -O-CH₂-(C₃-C₅) cycloalkyl, -CO₂H, -CO₂(C₁-C₄ alkyl), -CON₂H -CONH(C₁-C₄alkyl), -CONH(C₁-C₄ haloalkyl), -COKH(C₃-C₆ cycloalkyl) or NH₂; and R⁹ represents OH, -NHSO₂(C₁-C₃ alkyl), -NHCO(C₁-C₄ alkyl), -NHCO(C₁-C₄ haloalkyl), -NHSO₂(C₁-C₃ haloalkyl) or -NHSO₂(phenyl). Also, the invention refers to a pharmaceutical composition based on the compound of formula (I) which exhibits bovine and swine adrenergic beta-2-receptor agonist activity.

EFFECT: there are produced new compounds showing effective biological properties.

12 cl, 101 ex