FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a compound of formula
, or its pharmaceutically and veterinary acceptable salts, where: A represents -CH2-; and B represents -CH2-, -C(CH3)2-; or -A-B- represents -CH=CH-; one of R1 and R2 represents CH3 and another represents H; R3, R4, R5, R6 and R7, each is independently selected from H, R8 and R9; or R4 and R5 together represent -OCH2-CH2-, -CH2-CH2-O- or -O-CH2-O- and R3, R6 and R7, each represents H; R8 represents halogen, -CN, C1-C4alkyl, C1-C4haloalkyl, -CH2OH, -O-(C1-C4 alkyl), -O-CH2-(C3-C5) cycloalkyl, -CO2H, -CO2(C1-C4 alkyl), -CON2H -CONH(C1-C4alkyl), -CONH(C1-C4 haloalkyl), -COKH(C3-C6 cycloalkyl) or NH2; and R9 represents OH, -NHSO2(C1-C3 alkyl), -NHCO(C1-C4 alkyl), -NHCO(C1-C4 haloalkyl), -NHSO2(C1-C3 haloalkyl) or -NHSO2(phenyl). Also, the invention refers to a pharmaceutical composition based on the compound of formula (I) which exhibits bovine and swine adrenergic beta-2-receptor agonist activity.
EFFECT: there are produced new compounds showing effective biological properties.
12 cl, 101 ex
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