FIELD: medicine.
SUBSTANCE: new natural version of ghrelin predecessor resulted from an alternative gene splicing is described. A recombinant DNA method has been used to produce an active protein coded by said splicing version and showed ability to reduce body weight and food intake level after been analysed for functional properties on animal models.
EFFECT: using a new version of ghrelin and its active fragments for the purpose of preparing drugs for obesity or diabetes is offered.
7 cl, 28 dwg, 7 tbl, 4 ex
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