METHOD OF TREATING CRITICAL ISCHEMIA OF LOWER EXTREMITIES OF VARIOUS GENESES Russian patent published in 2011 - IPC A61K31/495 A61K31/137 A61P9/10 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to surgery, and concerns treating the patients with critical ischemia of lower extremities of various geneses. That is ensured by a complex background therapy of lower extremities involving intravenous drop introduction of SEROTONIN ADIPINATE 10 mg/day for 10 days with Mexicor added. For the first five days, Mexicor is administered once a day intra-arterially through a femoral catheter on an affected side in a daily dose 800 mg at rate 200 mg/hour. For the following five days, the intravenous drop introduction of Mexicor is performed by the schedule: at 6 o'clock - 200 mg; at 14⁰⁰ - 300 mg; at 22⁰⁰ - 300 mg dissolved in physiologic saline 100 ml at introduction rate 200-300 mg/hour.

EFFECT: method provides effective treatment and reduced number of failures in the form of amputation of the extremity due to improvement of microcirculation and elimination of reperfusion disorders in ischemic tissues.

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