FIELD: chemistry.
SUBSTANCE: invention relates to novel oxadiazole compounds of formula (1) and pharmaceutically acceptable salts thereof, where R1 and R2 assume values given in the description, Y is a single bond. The invention also relates to use of said compounds as DGAT1 inhibitors, for example for treating obesity and diabetes, and a method of inhibiting.
EFFECT: high treatment efficiency.
13 cl, 65 tbl, 712 ex
Title | Year | Author | Number |
---|---|---|---|
NOVEL PHARMACEUTICAL USE OF THIENO[3,2-D]PYRIMIDIN-4-ONE COMPOUNDS | 2019 |
|
RU2768828C1 |
COMPOUNDS OF THIENYL[3, 2-d]PYRIMIDINE-4-ON, METHOD FOR PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR APPLICATION | 2012 |
|
RU2624021C2 |
METHOD OF RESIDUAL LIPOPROTEINS PRODUCING INHIBITION | 2004 |
|
RU2330682C2 |
COMBINED THERAPY INCLUDING SGLT INHIBITORS AND DPP4 INHIBITORS | 2009 |
|
RU2481106C2 |
AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID DERIVATIVE | 2009 |
|
RU2481343C2 |
METHOD FOR TREATMENT OF STATES CAUSED BY p38 KINASES AND PYRROLOTRIAZINE COMPOUNDS USED AS KINASE INHIBITORS | 2001 |
|
RU2316556C2 |
DERIVATIVES SHOWING PPAR-RECEPTOR AGONIST ACTIVITY | 2006 |
|
RU2415846C2 |
IMIDZOL DERIVATIVE CONDENSED HETEROCYCLE HAVING ACTIVE AMPK EFFECT | 2011 |
|
RU2635662C2 |
MONOMER DERIVATIVES OF GLYCOPEPTIDE ANTIBIOTIC | 2005 |
|
RU2424248C2 |
TYPE 1 DIACYLGLYCEROL-O-ACYLTRANSFERASE ENZYME INHIBITORS | 2008 |
|
RU2486186C2 |
Authors
Dates
2011-06-20—Published
2005-12-09—Filed