OXADIAZOLE COMPOUNDS, USE THEREOF IN PREPARING MEDICINAL AGENT AND METHOD OF INHIBITING DGAT1 ACTIVITY Russian patent published in 2011 - IPC C07D271/113 C07D413/12 C07D413/14 A61K31/4245 A61K31/4545 A61K31/495 A61K31/5375 A61K31/54 A61P3/04 A61P3/10 

Abstract RU 2421451 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel oxadiazole compounds of formula (1) and pharmaceutically acceptable salts thereof, where R1 and R2 assume values given in the description, Y is a single bond. The invention also relates to use of said compounds as DGAT1 inhibitors, for example for treating obesity and diabetes, and a method of inhibiting.

EFFECT: high treatment efficiency.

13 cl, 65 tbl, 712 ex

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RU 2 421 451 C2

Authors

Berch Alan Martin

Bauker Suzann Sakson

Batlin Rodzher Dzhon

Donal'D Krejg Sehmjuehl'

Makkoll Uill'Jam

Novak Torsten

Plaurajt Allin

Dates

2011-06-20Published

2005-12-09Filed