IMIDZOL DERIVATIVE CONDENSED HETEROCYCLE HAVING ACTIVE AMPK EFFECT Russian patent published in 2017 - IPC C07D471/04 A61K31/4188 A61K31/437 A61P3/10 A61P3/04 

FIELD: chemistry.

SUBSTANCE: invention relates to a heterocyclic compound of the formula (I), or a pharmaceutically acceptable salt thereof, wherein the group represented by the formula is a group represented by the formula: ; R¹, in each case, independently, is halogen, unsubstituted alkyl, substituted alkenyl, substituted alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocyclyl, or substituted amino; wherein the said radical values are disclosed in the invention formula; m is an integer of ² or 3; ^R2 is hydrogen; X is -O-; and Y is substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; where the said values of the radical are disclosed in the invention formula. The invention also relates to the pharmaceutical composition based on a compound of theformula (I) and the method of preventing or treating diabetes based on the compound use of the formula (I). .

EFFECT: new compounds have been produced that have an activating effect on adenosine monophosphate-activated protein kinase.

18 cl, 87 tbl, 24 ex