METHOD OF PRODUCING RIBOFURANOSYL-PYRIMIDINE NUCLEOSIDES Russian patent published in 2011 - IPC C07H19/06 C07H5/02 

Abstract RU 2421461 C2

FIELD: chemistry.

SUBSTANCE: method enables to obtain 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one of formula (IV), which is a strong inhibitor of NS5B polymerase of hepatitis C virus (HCV).

EFFECT: high yield.

2 cl, 4 ex

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Authors

Ehkst Stiven D.

Sarma Keshab

Vajtehjl Dzhastin

Chzhu Tszjan

Ross Brjus

Rachakonda Suguna

Tszin' Tsinvu

Chun B'En-Kvon

Dates

2011-06-20Published

2007-10-05Filed