HCV-ACTIVE 4'-ASIDONUCLEOSIDES Russian patent published in 2015 - IPC C07H19/67 A61K31/7072

Abstract RU 2556991 C2

FIELD: medicine.

SUBSTANCE: present invention refers to compounds for treating viral hepatitis of formula: , wherein R¹, R² and R³ are independently specified in hydrogen and C_1-6alkylcarbonyl; provided at least one of R¹, R² and R³ are different from hydrogen, and provided a compound according to formula I is other than (2R,3R,4S,5R)-4-acetoxy-5-acetoxymethyl-5-azido-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester of acetic acid, as well as to their pharmaceutically acceptable salts and based pharmaceutical compositions.

EFFECT: there are presented new effective agents for treating hepatitis C virus infection.

12 cl, 9 ex, 8 dwg

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RU 2 556 991 C2

Authors

Ma Khan

Sarma Keshab

Smit Dehvid Bernard

Dates

2015-07-20—Published

2011-01-25—Filed