METHOD OF TREATING DENGUE FEVER Russian patent published in 2016 - IPC A61K31/7068 A61K31/7072 A61K31/7076 A61K31/708 A61P31/12 C07H19/10 C07H19/20 

FIELD: chemistry.

SUBSTANCE: invention relates to compounds used in pharmaceutical compositions for treating diseases caused by dengue virus, having formulae: , where: R¹ is aryl, where said aryl is phenyl or naphthyl, optionally substituted with one or three substitutes independently selected from a group consisting of following: C_1-6alkoxy; R^1a is C_1-6alkyl; R^1b is -OR^1a or -N(R^1a)₂; R^2a and R^2b (i) are independently selected from a group consisting of following: hydrogen, C_1-10alkyl, -(CH2)_mC(=O)R^1b and aryl-C_1-3alkyl; R³ is C_1-10alkyl or aryl-C_1-3alkyl, where said aryl is phenyl; R⁴ is hydrogen; R⁶ is A, B, C or D, where R⁸ is hydrogen or C_1-3alkyl; R⁵ and⁷ are independently selected from hydrogen, C(=O)C_1-6alkyl; m ranges from 0 to 3; or its pharmaceutically acceptable salt.

EFFECT: treating diseases caused by dengue virus.

19 cl, 2 tbl, 2 ex